The Cannabis Oil Suppository Debate: Personal Testing & Results

Using cannabis to treat medical conditions is gaining in popularity and acceptance every day.  While smoking, vaping, edibles, and topical applications are very familiar the use of suppositories is still in the shadows and a relatively unknown alternative.  After learning about the success many people claim to have with suppositories I decided to bring this helpful information to the masses.  I quickly learned, and was shocked to find, that the effectiveness of cannabis oil (CO) suppositories was a topic of heated debate!  Suddenly, my idea of a quick and easy informational post ballooned into an amateur research exercise and science project to identify points in the debate I could confirm, dispel points that didn’t checkout, and develop a better understanding of the topic in general.  This post I endeavors to explain many things about CO suppositories; what the debate over effectiveness is about, possible benefits, physiology involved, personal testing experience, what my experience proved to me, and what a blood test showed about absorption.

WHAT’S THE DEBATE ALL ABOUT?

Medication administered rectally in the form of suppositories is used in general medicine to provide a rapid, very efficient uptake and absorption into the circulatory system.  CO suppository advocates propose that the same applies to the efficiency of THC uptake and it can reach up to 70% with suppositories while oral ingestion and smoking top out at around 20%.  The other side of the argument contends that the high uptake efficiency attributed to suppository medication only occurs when the delivery medium is water soluble or is aided by an additive to increase absorption, and accordingly oil based material alone can’t be absorbed through the thick mucus and wall of the lower rectum.  Therefore, the naysayers say homemade CO and coconut oil suppositories can’t be absorbed in any meaningful concentrations and maybe not at all.  Whether or not oil-based compounds like CO alone can be efficiently absorbed through the lower rectum is the crux of the entire debate.

WHAT WOULD BE THE BENEFITS OF CO SUPPORITORIES?

There are two key attractive benefits of suppository use.  One benefit is the high efficiency and bioavailability of rectally administered meds.  If the absorption efficiency can reach 50%-70% the cost effectiveness per volume of CO used is very desirable and would provide substantially more medicine for the same money.  Moreover, the ability to deliver a higher dosage of CO to the blood and areas requiring treatment would be greatly enhanced.

Second, and more complex, is the benefit of avoiding most, or all, psychoactive effects of THC.  The psychoactive effects from smoking or orally ingesting CO can be so devastating for some users that they’d rather forgo using CO despite any potential it may have in their treatment.  If large amounts of THC were able to be absorbed without psychoactive effects many people who currently can’t medicate with CO could enjoy its healing powers.

The lack of psychoactive effects of THC is interpreted very differently by the proponents and the doubters in this debate.  Proponents say if a suppository is administered properly, in the lower section of the rectum, the THC is absorbed in a way that avoids psychoactive effects.  The other side of the debate points to the lack of psychoactive effect as proof that the CO is simply not being absorbed and distributed through the circulatory system.  I needed a lot more information because I had zero knowledge concerning the physiology of the rectum or how it functions within the circulatory system so I started searching for answers and asking lots of questions.

RECTAL PHYSIOLOGY, BLOOD FLOW, AND DRAINAGE WITH RESPECT TO SUPPOSITORY ABSORBTION, METABOLISM AND THC INDUCED PSYCHOACTIVITY?

The physiology, drainage and blood flow away from the rectum differs between the upper and lower sections.  Understanding the differences between the upper 1/3rd and lower 2/3rds of the rectum gives clarity to why a CO suppository in the lower rectum could circumvent the onset of psychoactive effects brought on by THC absorption.

The upper 1/3rd of the rectum is part of the hepatic portal system where nutrients are absorbed, drainage occurs through the portal vein, the blood is transported to the liver and metabolized by the liver, then onto the heart for general distribution to the body. When delta-9-tetrahydrocannabinol (THC) passes through the liver some is metabolized into the stronger and more psychoactive 11-hydroxy-THC.  Oral consumption of CO essentially follows this same flow through the liver, referred to as first pass metabolism. Higher pressure in the upper region of the rectum more readily facilitates oil based medicine absorption and can be tested by putting some CO way up there and letting the psychoactive circus begin.

The lower 2/3rds functions much differently.  This section drains to the internal iliac vein which bypasses the liver and is delivered to the right atrium of the heart, to join the systemic circulation, and off to the body.  Advocates of the CO suppositories say that by missing the liver this way the lack of THC metabolites greatly limits or eliminates psychoactive effects of THC.  Contrarily, the naysayers argue that the pressure in this area is too low, the mucus wall too dense for oil based medication to be absorbed, and therefore the lack of psychoactive effect is due to the medicine not being absorbed in any meaningful amount, if at all.

BOTH SIDES MAKING SENSE?

I was conflicted because I really wanted suppositories to be the missing link to healthy consumption of CO, however, both sides of the argument seemed to be making sense and I needed to find more reliable information to base a conclusion and then share with those who may be as confused as me.  In searching for information and guidance I found plenty of anecdotal third party stories, testimonials, and a few often referenced studies that were either flawed or introduced elements that made them incompatible with analysis of the use of suppositories made with only CO and coconut oil.  I was so deep in hearsay and tainted information the only way to form an opinion about this subject was to test it on myself.

WHAT I WANTED TO LEARN BY TESTING

First, I wanted to determine what kind of physical or psychoactive effects I would experience by using CO suppositories.  Second, I wanted to find a definitive way to establish if THC was absorbed into the bloodstream and if it was absorbed what was the concentration and constituent make up?

PLAN FOR TESTING

The goal for pre-test preparation was to cleanse my blood of any residual THC.  THC for a single use is estimated to stay in the blood for 12-24 hours while those who use cannabis on a regular basis can expect TCH to remain in the blood for nearly a week.  To ensure there would be no trace of THC in my blood prior to the experiment I abstained from anything cannabis for 2-weeks.  Clean blood was crucial for the accuracy of the cannabinoids blood screen (test code 8421) to evaluate THC absorption and shed light on any other useful information that might indicate CO efficiency.  Abstaining ahead of the testing would also increase sensitivity to any physical or psychoactive effects brought on by the suppository testing.

The execution stage of the experiment would include taking one 2ml 20mg THC suppository the evening prior to the blood test to evaluate any physical and psychoactive effects.  At 8 a.m. the next morning I planned to take a second 2ml 20mg suppository to reevaluate and compare the effects to the night before.  Finally, I would conclude the experiment with a blood test 4 hours later in hopes of catching any current THC absorbed near its peak and any residual THC metabolites from the night before.

MAKING SUPPOSITORIES

Before I could start testing on myself I had to learn to make suppositories.  In preparation I ordered 2ml disposable suppository molds from Amazon.  Once the molds arrived, I made 0.8g of CO using the Source (making FECO with the Source by ExtractCraft), combined it with 50g of coconut oil (the type that returns to solid form at room temperature), filled 28 disposable suppository molds, then put the molds in the freezer to solidify and store.  Assuming the CO I made was approximately 70% THC the suppositories were 20mg each.  For clarity, as in the linked FECO making instructions, I used decarboxylated material to increase the bioavailability of THC.  I was happy to find that making the suppositories myself was pleasantly simple and rewarding.

IMG_4352

(Side note: suppository molds are awesome for storage! You can make a bunch of frozen, premeasured doses for oral consumption or for cooking. The frozen coconut oil and CO in that shape are very easy to handle and use.)

EXECUTION OF THE TESTING

With cleansed, THC-free blood it was time for truth, an unbridled search for scientific knowledge, and putting something where nothing has ever been put before.  At 6 p.m. I put on the recommended latex glove, inserted the suppository just inside the sphincter, no more than 1 ½ inches inside, making sure it stayed in the lower area of the rectum, laid on the bed for a few minutes hoping I did it correctly and very thankful the kids didn’t come barging in at the most inopportune time.  The process was very simple and much less stressful than I anticipated.  After a few minutes I stood up, half expecting something to come shooting out, but much to my relief everything seemed very normal.

After 10-minutes the effects undoubtedly showed the first signs of effectiveness with an almost imperceptible body calming sensation.  By the 30-minute mark a full body calming was in full effect.  It wasn’t a strong, stony body high, but more like the comforting feeling of being tension free and wrapped in a warm blanket.  I also recognized a sensation in my mouth and jaw that I often identify with cannabis consumption.  There was an interesting, very slight feeling creeping up the back of my neck that felt like the CO was flirting with imposing a head-high but it held short and left me clear headed the entire time.  My body was high, my psyche was soothed, and my ability to reason untouched.  Finally, when I turned in for the evening I was well relaxed and had a solid, serene night sleep.  I woke up with ease the next morning and felt great with none of the hangover effects often associated with edibles.  After getting around and completing my morning duties it was time for the 8 a.m. dose.  I followed the same procedure as the previous night and was once again surprised by how easy the process was.  The effects of the morning dose were an exact repeat of the night before.  It made for a very pleasant, relaxed, clear headed, and pain free morning.  At around noon (4-hours later) I had my blood drawn for the cannabinoids blood screening.  A little later, in the early afternoon I became tired and at 2 p.m. I took one of the best naps of my life.  I woke up from the nap feeling great, perfectly clear headed, with all discernable sensations of the CO gone.  From the feedback my body provided there was no doubt in my mind the CO had been absorbed and had worked its magic on me.  With the blood test finished, the experiment was complete and the only thing left to do was to wait 7-10 days for the results.

BLOOD TEST

I was very excited anticipating the results of the blood test because regardless of what the results indicated it was going to be very interesting.  If the test showed significant uptake and absorption of THC it meant many people could feel confident that CO suppositories did in fact deliver the medicine in an effective way.  On the other hand, if the results indicated negligible or no absorption at all we would have a mystery on our hands to explain what was responsible for the physical effects experienced during testing?

Seven days after having my blood drawn for the test I received the results:

DELTA 9 THC………………………NONE DETECTED < 1.0 MCG/L

11 HYDROXY DELTA 9 THC……NONE DETECTED < 1.0 MCG/L

11 NOR 9 CARBOXY THC………6.38 MCG/L

Suppository Testing Blood Test

 

CONCLUSIONS

First, I was able to identify definite physical effects of the CO suppositories but no psychoactive effects at all.  The physical effects I identified left little doubt that absorption of the CO defiantly took place.  How much absorption took place was hard to judge because I’ve never before experienced a body-high in the absence of a head-high.  My experience with the disjointed body-high supports the idea that when administered in the lower area of the rectum any THC absorbed bypasses the first pass metabolism, misses the liver, and therefore has little to no psychoactive effect.  My unscientific support of this idea comes from the imbalance of what my body and head experienced, therefore, I reasoned if the distribution of THC was in balance, like with smoked or orally ingested CO, I believe I would’ve had a strong head-high to match what was going on with my body.

Second, I needed to establish if THC was actually absorbed into the bloodstream, and if it was what was the concentration and constituent make up.  Unfortunately, the blood test results were in direct conflict with my unscientific conclusions based on physical experience alone.  The blood test clearly showed that 4-hours after the use of the 20mg CO suppository made with coconut oil there was no detectable THC or its first metabolite 11-hydroxy-THC.  There was a low level of 11-nor-9-carboxy-THC, the second metabolite, which could be minor evidence of absorption or simply residual THC remaining from more than 2-weeks prior to the testing.   Due to the fact that both delta-9 THC and 11-hydroxy-delta-9 were not detected at all, the origin of the low level presence of 11-nor-9 carboxy THC can be debated and is definitely worthy of some follow-up research.  Next time a blood test should be added to the experiment before using any CO to establish a reliable benchmark against the post consumption results to be compared for absolute certainty of the metabolite origin.

Unfortunately, my conclusion is almost as confused as my understanding of the topic was when I began this project.  I think it’s clear that for people with medical conditions requiring treatment in the pelvic area where the suppository can deliver the CO directly into contact with the needed treatment area it would be advantageous to use CO suppositories.  For those treating pain, stress, depression, general well being and would like to forego the head-high associated with THC I would highly recommend giving CO suppositories a try and judge the effectiveness for yourself.  For severe illnesses like cancer, where high levels of THC penetration is absolutely required I can’t ignore the blood test results.  At best I would say its worth using in combination with other modes of CO ingestion but the results clearly demonstrated that the necessary delivery of THC is not occurring.

NOTES

I highly encourage everyone to give it a try and let me know about your experiences.
Everything in this blog is simply my opinion and based on my personal experimentation and not as a medical professional. Any recommendations I make should not be taken as medical advice and before following any recommendations in this blog you must consult with your doctor. Don’t consume anything you are not familiar with and hasn’t been cleared with your doctor.
It is imperative that you know and abide by the laws governing your area concerning cannabis and any processing of cannabis.

 

I recommend the Source by ExtractCraft at www.extactcraft.com for safe, high quality home extraction.  Coupon code “IBC100” for $100 discount.SourceTurboDebutFBCover copy

STAY SAFE, HEALTH, FREE AND LIFTED

51 thoughts on “The Cannabis Oil Suppository Debate: Personal Testing & Results

    1. Hello,
      My father has Multiple Myeloma, and we have been doing between .5-1 gram of pure oil insertion by syringe. In 9 weeks, my father’s cancer numbers came down from 24 to 2.7 (desirable is 0). We are very pleased. From what I’ve read, I thought rectal administration is 70% more bioavailable. He couldn’t tolerate eating the oil. he was also on some mild

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      1. That’s great news about your father! Im glad he is on the mend with the help of the oil. Did your father use only cannabis oil or were there other forms of medical treatment? The higher bioavailability is assuming the substance is able to be absorbed it’s not a given for all compounds.

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  1. Hello,I have been using this same method for over a year. I am an arachnoiditis victim, an incurable man made disorder which can qualify to belong to spinal injury. The damages in my spine is located at L5S1. The pain radiates, in a good day, from the lower back, around the right hip, groin, thigh, leg and foot. It is an intractable and debilitating pain.
    I was very skeptical at first and to say the least reluctant to use the rectal route. Nevertheless, I started medicating this way.
    The result is wonderful in a sense that the pain is diminished or gone, depending of my daily activities. I used to have a beautiful body sensation, your description of being embraced with a warm blanket is an exact description. This feeling has gone now, as I suspect my body has become accustomed to cannabis. The psychoactive feelings are none existent, therefore it allows me to drive, to read, to speak properly, to think logically.
    I know that there is a debate. I don’t care what the findings are because it works for me. The quality of life that I have acquired is almost a miracle. No more wheelchair, no more toxic prescriptions of medications leaving me like a zombie. And so it is about the results, the beneficial effect of cannabis that is important. It is also important to value and retain the user’s experience . Negating this facet of the equation is negating the patient’s injury/pain. It is following the same paradigm that the patient ‘s experience is not valuable and not believable because the tests demonstrate the opposite. Modern medecine has created this paradigm, it should be be carried over to alternative medications.
    Regardless of results, I will not stop using this method simply because it works, period.
    Looking forward to read more answers to your experience. Have a good day

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  2. I am a cancer patient, metastatic bone cancer, I’ve done the rick Simpson 60ml course over 90 days and I now take medicinal dose of 6 rice grains per night, I have a scan on 12th June so I’ll know then if it’s helped.

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  3. I agree, there is definitely something there.

    I, too, used CO 50/50 w coconut oil. I did 1 gr rectally, and .25 orally. I am current cancer free, and only doing the oral,dose now.

    I’ve dosed both shallowly and deeply. When I dose deep, I get the head high, but I don’t think it’s as debilitating as oral dosing.

    Is still it possible that it’s so completely absorbed that there is nothing left to show in the bloodwork? I wonder because obviously something is absorbing. Maybe do an entire gram and then do your blood test?

    I appreciate you’re attempt to shed some light on the subject!

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    1. I don’t think it is possible for everything to be absorbed, used, and eliminated in 4-hours. But it is crazy how you can defiantly feel it, but the blood says nothing. I think doing the full gram would be a good idea just to see what happens, but them my current understanding of the anatomical functions, 20mg should have shown up fine.

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  4. Thank you for doing this testing and sharing your results. This information is very helpful, as is the comment by reader Louise.

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  5. Interesting research, thank you for posting.

    I can think of two questions that need to be raised: 1) Is the THC being metabolized into some chemical that the test does not show, and/or 2) Is the THC traveling through the lymphatic system instead of the blood??

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    1. Anything is possible but what would that chemical be and what would be the mode of metabolism? I’m not sure about the lymphatic circulation scenario.

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  6. I think the best experiment might be to compare regular thc suppositiorities & the THC-HS suppositiories & thc metabolite blood levels in the same patients. There is something funky going on with the variety between some patients having absorption & some not, as least via the measure of blood tests. We need to identify why some patients are “nonrepsonders,” and whether blood levels of THC metabolites is the valid measure of efficacy for rectal suppositories.

    I’d be happy to run some of these studies with funding in the future, as a neuroscientist & director of IMPACT Network.

    Liked by 1 person

    1. To make certain you are comparing apples to apples a sampling of the suppositories should be lab tested. It is easy to screw up decarboxilation. The THC Acid may never have become THC, or degraded into other canabinoids or maybe even vaporized off.
      I think that is at least as probable as classes of different humans with significantly different absorption quotients.

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      1. I agree that for accurate scholarly work this should be done. In amateur, ad hoc science project contained in this blog I can assure you the material was properly decarbed. It may not have been perfectly decarbed to lab spec, but it was good representation of real world at home decarb and I say this for two reasons. First, I have decarbed many times in many ways and have some experience in the exercise. Secondly, I ate half of one after the experiment just to confirm to myself they were in fact decarbed well, and I can again assure you they were as it took me on a very pleasant edible ride.

        Side note: I mentioned that the suppository molds work very well for storage of remeasured oral dosage. What I didn’t mention is that they are really nice and easy to consume orally as well. They are a little crunchy, not solid rock like you would suggest, really light in the mouth and very pleasurable. Having said that, the pleasant oral experience is also because I use a pretty clean FECO extraction as apposed to the green sludge that some people use.

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      2. Hey, I wasn’t knocking the effort. I just have a lot of experience in learning from my mistakes. The feeling he described, sounded a lot like CBN, which is what THC degrades into when over-heated. Possible CBN is easier to absorb from the membranes in that region. At any rate I’d be curious if they could retest his previous blood sample, looking for CBN.

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      3. There is no problem here, thank you for your input. I get what you are saying, but I would not equate the feeling with CBN directly. If anything not THC it was more like CBD with the pain relief and calming that can come with that. Having said that, the feeling is something I would attribute to THC and comparable sensations I am familiar with from past experience, just with the absence of psychoactive effects. As for CBN being a form that wold be more readily absorbed in comparison to THC I don’t know the answer to that. It would be worth taking a look

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  7. Thank you. I have been making these with Cacao butter, as I had no luck with coconut butter. Given that Coconut butter was stated at the beginning of your post to be a possible impediment to absorption I was surprised you used it for your trial. Have you triwd a water based carrier? What might that be? I have tried straight thc/cbd oil, from a soft syringe applicator, but prefer suppositories. Cacao butter seems to help… it has the same hardening/softening properties as Coconut oil…

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  8. Thank you for the efforts of both trying and documenting this. I have only just received my Medical Marijuana license (CAnada) and have tried both 1:1 oil and CBD (virtually no THC) oil. Sorry – I”m not sure of all the “proper” terms yet. Even starting low and slow, I am Not a fan of the disorientation or other feelings of the higher THC, but I have Fibromyalgia which over the years has left me in constant often debilitating pain, insomnia, CFS… and all their various friends. I am hopeful cannabis will be able to help me, as I”ve heard it has worked so well for others. So i had a look into rectal administration and my research led me to your article here. The oils I receive are from Cannimed, and I can only hope they’re of good quality. Does the oil have to be combined with Coconut or other (cacao) oils to assist the absorption? Or can the oil simply be inserted without the carrier oils. I work at a vet clinic and have access to different syringes etc…
    I would love to hear your thoughts on this – thank you!

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    1. Thank you for your question and I hope you find the relief you seek. The coconut oil serves two purposes. First it allows you to dilute the potency and control dosage. Secondly, it serves as a forming medium to create the suppository shape in the mold. Neither use of coconut oil as necessary and a syringe delivery should accomplish the same ends. Many people are using syringe delivery it’s just a matter of choice I suppose

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  9. I have been experimenting to make cannabis suppositories since I need it to relax my puborectalis for anismus and so I thought rectal administration would make more sense. I also need it for fibromyalgia, IBS etc. However I have had many mishaps in the sense of irritability.

    First I tried coconut oil which gave me bloating, then I tried organic cacao butter but it still irritates my bowel and gives me constant urge of bowel movements even hours after insertion (and only oil comes out). Is there any other ingredient I can use that does not irritate. I mix these bases with FECO.

    Apart from the irritation I prefer the way cannabis works when taken rectally rather than orally because I remain alert ,no dizziness or high feeling.

    Thank you.

    Liked by 1 person

  10. I am trying to make CBD suppositories. Can CBD concentrate powder be used in place of CBD oil tincture? And when mixing it into the melted base (cocoa butter or coconut oil), is there anything different I should do? Thank you.

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  11. I am trying to make CBD suppositories myself. Is it suitable to use CBD concentrate powder in place of CBD oil tincture? And when mixing it into the melted base (cocoa butter or coconut oil) is there anything I should do differently? Thank you.

    Liked by 1 person

      1. First off are you in Canada or the US if in Canada I have been taking the oils from health Canada orally and it has brought my psa score down

        Liked by 1 person

      2. I am in the US. Oral consumption is the most common delivery and least controversial. It’s awesome to hear you are on the mend. I wish you a speedy recovery. Thank you or sharing

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      3. Yes, that makes sense. I am not medically trained but I have seen information pointing to the same thing. I have also seen studies that are evaluating the effectiveness of THCA on prostate cancer, which is different from the traditional use of high dose THC to fight against most other cancer. Unfortunately, he real and solid research is thin so like yourself we are all just doing what we can to find out what works best on an individual basis. I have not used CBD powder concentrate personally so I can’t report from first hand knowledge but I would think it will deliver just fine by melting into the coconut oil and making the suppositories. I truly wish you the best and wish for your father’s speedy recovery.

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  12. Do you have experience, know of anyone, or articles where cannabis shatter can be used for making suppositories with gel caps? I plan to make suppositories by melting down cannabis shatter and diluting with coconut oil then filling up gel caps. I plan to use the Harlequin and Green Crack sativa strains for energy.

    I would like to read learn more about making suppositories from shatter and using gel caps instead of suppository molds. I have not made cannabis suppositories before and am not aware of anyone or resource with making suppositories from cannabis shatter and using gel caps before.

    I am trying to create a treatment for aggressive stage 4 pancreatic with lesions on the liver and suspicious cells on the lungs diagnosed 8/8/17. Currently, there are no traditional treatment protocol options and oncologists have said time is short and anything can happen anyway as the cell growth is aggressive and will continue to disrupt other body function.

    I want treatment for inhibiting cell growth, cell destruction, pain, energy and appetite stimulation along with sleep aid. I have been using the Rick Simpson oil for a week and it has helped greatly with sleep with some appetite stimulation.

    Any information shared by any would greatly appreciated.

    Thank you.

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    1. Hi Mai,
      Making suppositories with either molds or gel caps using shatter is the same as using cannabis oil in any other form. It will incorporate quite readily with the carrier. I’m not sure what the advantage of using gel caps would be, the molds are very easy and convenient. I am absolutely not a medical professional so please don’t take anything I say as credible advise because it isn’t. From my experience with my amateur testing, if I were treating myself for lung and liver I would be ingesting the CO orally. Personally, if it isn’t something that would be in direct contact with anal delivery I would treat orally. Are you thinking to use both orally and with suppositories? Are you vaping at all for appetite and pain?

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  13. Dear Ichibancrafter,
    My husband and I were ecstatic to hear of the possibilities of suppositories to help cure my FIL’s very rare thyroid cancer. After a lot of internet research (roll of eyes lol)…we’re coming to realize there is not nearly enough research supporting the actual absorbtion of THC into the bloodstream through the rectum due to the fact that it is oil based. Your article and experiment proved to be very insightful for us and I thank your that. My FIL’s life depends on the accuracy of our amateur research tactics. It seems we have to do it it the way Rick Simpson intended and hope my FIL can withstand the high. Or find enough that we can afford to do it both rectally and orally…still left with the issue that he’s gonna be very high. Thank you for clarifying what you could for us.

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    1. I’m glad I could help with the little I was able to do. Once people get used to the “high” most can deal with it pretty well, its letting go and not freaking out about it the first few times that you have to get past. If he doesn’t like the high, which many don’t, you can try a few things that might help. Obviously, start with just a tiny bit and increase as you are able. Another would be administering right before going to sleep, by the time it kicks in he will already be sleeping. This may sound counterintuitive, but, you could try to give him a larger dose that will just knock him out. Unfortunately, the psychoactive effects after oral ingestion last for comparably long duration. Maybe he might want to try smoking some for a few times to get a close approximation of what it will feel like to test the waters. The good thing about smoking is the peak is just a handful of minutes after smoking, you are mostly unaffected after 60-minutes and 90% of any effects are gone in 90-minutes. Just some ideas, hope it helps.

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    2. Take your time building up tolerance remember even if your starting out on small doses the medicine is working just need to build up the tolerance to be able to enjoy the full benefits of the medicine it really does not take too long

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  14. Thank you for this in depth article. May I ask a question that I cannot find the answer to anywhere.
    What is the difference in efficacy not formulation between RSO and FECO extracted into ghee, coconut oil, or any other carrier.
    Aren’t they the same product just Extracted differently? Thank you

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    1. Annie, thank you for your question. You kind of mixed a whole bunch of things together in one category there that are very different. First, RSO and FECO are drastically different in terms of the solvents used. RSO uses naphtha which in my opinion is a very big mistake and should not be used. You can see more on that in this blog post https://extractcrafter.com/2016/06/04/rso-feco-using-the-source-home-healing/ .

      Secondly, when you say “extracted into ghee, coconut oil, or any other carrier” I think you are lumping “extraction” and “infusion” into the same basket and especially as far as efficiencies go these are very different. You can read about the different in the section “Extraction vs Infusion” of this blog post https://extractcrafter.com/2017/09/12/understanding-the-source-turbo-by-extractcraft/ .

      Lastly, if you are talking about efficiency of absorption of the different carrier oils that is another subject where the saturated fats in most cases are better for absorption, but not in the case of suppository and anal absorption.

      I hope this help clarify what you were looking for, if not let me know and Ill take another crack at it!

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      1. So if “saturated fats in most cases are better for absorption, but not in the case of suppository and anal absorption”, what carrier oils should be used when mixing FECO to make suppositories?

        Thank you.

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      2. That is exactly the problem, and basis of the debate. In the case of suppositories it is the oil based nature of the cannabis oil itself that may suppress absorption, hence the carrier oil used seems to be a moot point. If it is an affliction that would come into direct contact with the cannabis oil via anal delivery then the choice of carrier would also be essentially equal with the most pure mixture probably being the most effective.

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  15. Thank you very much for this article. Not only did I find it to be very informative and well-written, but it also demonstrates a rare, objective intelligence, and an admirable faculty of observation (one that we could all benefit from, in my experience).

    Good job! 🙂

    Like

    1. Aaron, thank you very much for your very kind words. I appreciate it very much, knowing what I’m doing makes a difference makes it worth all the effort!

      Like

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